Best Panini Mosaic Football Cards (Top 10)

Here’s a breakdown of the 2021 Panini Mosaic Football Cards and an analysis of why these cards have increased or decreased in value since the 2022 football season. 

You’d be surprised how much prices vary and the impact knowing your football history can make on picking the right cards to add to your collection. 

Here are our top 10 Best Panini Mosaic Football Cards:

By Player & Example: Best Mosaic Cards List

1. Trevor Lawernce (RC) – Mosaic Honeycomb 2021 PSA 10

Trevor plays for the Jacksonville Jaguars as the number one overall pick. He played college football at Clemson University, where he led the team to a national championship in 2018 and was a two-time consensus All-American. 

Improving each game, he continues to live up to the hype based on his long throws into the end zone. 

During the 2021-22 season, Jacksonville Jaguars was 1 (wins) – 15 (losses); however, in 2022-23, their record is 6 (wins) – 8 (losses). Again, he saw significant improvement between seasons since adding Trevor Lawrence to the team. 

2. Zack Wilson (RC) – Mosaic Genesis 2021 PSA 10

Zack plays for the New York Jets as the number two (second) overall pick. Injury during the 2022 season caused his card to go down in value as fans were curious if Zack Wilson would be able to return. Also, if he did return, would he still be at his prime and able to play at his fullest potential. 

As games went on, and he did return in the 2022 season, he got benched, having his backup ‘Mike White’ become the starter. Additionally, fans speculated that Zack Wilson turned into the backup Quarter Back (QB) due to his comments during a press conference. 

All impacted the value of his card as the hype and the demand from fans began to slow down. However, especially since he’s in his second year as a Quarter Back, expectations continue to increase, and patience continues to run out. 

3. Mac Jones (RC) – Mosaic White Sparkle 2021 PSA 10

Mac plays as the number 15 (fifth) overall pick for the England Patriots. After experiencing an ankle injury, Mac had to earn back his starting position as backup quarterback known as Bailey Zappe gave hope to the Patriots fans. He played college football at the University of Alabama and won the national championship in 2020. 

4. Justin Fields (RC) – Mosaic Green 2021 PSA 10

Justin plays for the Chicago Bears as the number 11 (Eleventh) overall pick. He played college football at Ohio State University, where he was a two-time Big Ten Conference champion and a two-time consensus All-American.

5. Najee Harris (RC) – Mosaic Reactive Yellow 2021 PSA 10

Najee plays for the Petersburg Steelers as the number 24 (Twenty-Fourth) overall pick.

He played college football at the University of Alabama, where he was a three-time national champion and a consensus All-American. 

6. Patrick Mahomes (RC) – Mosaic Blue 2021 PSA 10

Patrick plays for the Kansas City Chiefs as the number 10 (tenth) overall pick. He is making it into the playoffs multiple times a year. He played college football at Texas Tech University before being drafted by the Chiefs in 2017. 

7. Justin Herbert (RC) – Mosaic Pink Camo 2021 PSA 10

Justin plays for the Los Angeles Chargers as the number 6 (sixth) overall pick and continues to impress his fans with his talent. He played college football at the University of Oregon, where he was a two-time Pac-12 Conference champion and a consensus All-American.

8. Brock Purdy (RC) – Mosaic Draft Picks AUTO

He’s known as ‘Mr. Irrelevant’ due to being the 5th-round draft pick. He played college football at the University of Iowa, where he was a consensus All-American. 

George was the third-string quarterback who surprisingly beat Tom Brady during his first game (and NFL Debut). 

San Franciso 49er fans will never forget a moment, along with his parents, who were on the sidelines cheering for him. He’s now the starting Quarter Back and increasing in popularity due to his long preparation for this moment. 

He played college football at the University of Iowa, where he was a consensus All-American. 

9. Trey Lance (RC) – Mosaic Pink Camo PSA 10

Trey plays for the San Francisco 49ers as the number 3 (third) overall pick. However, he experienced a career-ending injury early in the 2022 season, causing his card values to drop and ending all the hype around how he would change the San Francisco 49ers. 

He played college football at North Dakota State University, leading the team to two national championships, and was a two-time consensus All-American.

10. Jaylen Waddle (RC) – Mosaic Reactive Orange PSA 10 

Jaylen plays as the number 6 (sixth) overall pick for the Miami Dolphins. 

He has the nickname ‘the penguin’ due to his last name and touchdown celebration dance where he ‘waddles’ for the Miami Dolphins fans. 

He played college football at the University of Alabama, where he was a two-time national champion and a consensus All-American. 

By Variation: Best Mosaic Cards List

1. Mosaic Honeycomb
2. Mosaic Genesis 
3. Mosaic White Sparkle 
4. Mosaic Reactive Orange 
5. Mosaic Reactive Blue 
6. Mosaic Pink Camo 
7. Mosaic Green 
8. Mosaic Yellow 

By Type/Parallels: Best Mosaic Cards List

• NFL Debut
• No Huddle (Disco) 

For more information on Parallel cards, we wrote an article on ‘What are Parallel cards & How do They Work” which goes in depth on what to look for when buying parallel cards. 

First Understand Why You Collect Mosaic Cards

It’s essential to think about why you are buying or adding a card to your collection. 

As a collector, search by player first and then see which variations are available to identify the best cards worth adding to your collection.  Then identify where to buy sports trading cards at an affordable price. 

For example, if you like Justin Herbert, it’s better to add his cards to your collection than Patrick Mahomes because his values are higher. 

The Justin Herbert mosaic card would be better for you even if the value is less since he’s your favorite player.  

We hope this list of the best panini mosaic football cards helps give you an idea of the variations and which players (2021-22 draft picks) hold their value the most. 

If you’ve enjoyed reading this article, you may also like the following: 

• How to Find the Value of Sports Trading Cards
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